Endocrine Abstracts

Background: Graves’ disease (GD) is an autoimmune disease caused by autoantibody targeting the thyrotropin receptor (TSHR) in the thyroid gland, resulting in hyperthyroidism with an annual incidence of 15 to 80/100,000 people worldwide. Current mainstream treatments for GD include aggressive treatment with radioiodine and thyroidectomy or unspecific immune-modulating therapy with glucocorticoids, antithyroid medications or anti-CD20 antibodies like Rituximab. Therefore, o...

Objective: To investigate the prevalence of hyperuricemia in Chinese population, and the association between serum concentrations of uric acid and related metabolic disorders.Methods: This study was based on de-identified hospital information system (HIS) data collected from four tertiary hospitals in three provinces of China. A total of 432,002 patients with at least one medical visit recorded SUA measurement were screened and 374,506 were enrolled. Hyp...